Article

Identification and validation of senescence-associated secretory phenotype-related biomarkers in epilepsy

2026-04-02

Abstract excerpt

<title>Abstract</title> <p>Epilepsy is increasingly linked to cellular senescence and the senescence-associated secretory phenotype (SASP), which propagates sterile neuroinflammation and tissue remodeling. However, the specific SASP-related molecular signatures driving epileptogenesis remain poorly characterized. Integrating human cortical transcriptomic profiles (GSE256068) with a curated SASP gene set, we ident...

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Literature Corpus work: 95d8efaa-cee9-5a93-b2bc-48073fea9576
DOI: 10.21203/rs.3.rs-9165812/v1

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