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Comprehensive analysis of senescence-related genes identifies prognostic clusters with distinct characteristics in glioma

19 Mar 2025

Abstract excerpt

Cellular senescence, defined as a state of permanent arrest in cell growth, is regarded as a crucial tumor suppression mechanism. However, accumulating scientific evidence suggests that senescent cells play a detrimental role in the progression of cancer. Unfortunately, the current lack of reliable markers that specifically reflect the level of senescence in cancer greatly hinders our in-depth understanding of...

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PMID: 40108265
DOI: 10.1038/s41598-025-93482-8

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