Article

Unraveling Epilepsy Biomarkers through Single-Cell Sequencing and GEO Data Integration: A Focus on Parthanatos Pathway

2025-08-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Epilepsy is a chronic brain disorder with complex molecular mechanisms. Parthanatos, a PARP-1-dependent programmed cell death pathway, has been implicated in neurodegenerative diseases and mitochondrial dysfunction, which are closely associated with epilepsy pathogenesis. However, the role of parthanatos-related genes (PRGs) in epilepsy remains unclear. This stu...

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Literature Corpus work: 2d3a244d-11c7-53ef-96f5-dac014babf24
DOI: 10.21203/rs.3.rs-7337638/v1

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