Article

Tick-borne flavivirus exoribonuclease-resistant RNAs contain a ‘double loop’ structure

2024-04-14

Abstract excerpt

<h4>ABSTRACT</h4> Flaviviridae viruses are human pathogens that generate subgenomic noncoding RNAs during infection using structured exoribonuclease resistant RNAs (xrRNAs) that block progression of host cell’s exoribonucleases. The structures of several xrRNAs from mosquito-borne and insect-specific flaviviruses have been solved, revealing a conserved fold in which a ring-like motif encircles the end of the xrRN...

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Identifiers and source

Literature Corpus work: 9592c64b-5733-5757-8ac1-3744c9dde151
DOI: 10.1101/2024.04.14.589432

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