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Subgenomic Flaviviral RNAs of Dengue Viruses

24 Nov 2023

Abstract excerpt

Subgenomic flaviviral RNAs (sfRNAs) are produced during flavivirus infections in both arthropod and vertebrate cells. They are undegraded products originating from the viral 3' untranslated region (3' UTR), a result of the action of the host 5'-3' exoribonuclease, Xrn1, when it encounters specific RNA structures known as Xrn1-resistant RNAs (xrRNAs) within the viral 3' UTR. Dengue viruses generate three to four...

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PMID: 38140548
DOI: 10.3390/v15122306

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