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Article

Different tertiary interactions create the same important 3D features in a distinct flavivirus xrRNA

1 Oct 2020

Abstract excerpt

During infection by a flavivirus (FV), cells accumulate noncoding subgenomic flavivirus RNAs (sfRNAs) that interfere with several antiviral pathways. These sfRNAs are formed by structured RNA elements in the 3′ untranslated region (UTR) of the viral genomic RNA, which block the progression of host cell exoribonucleases that have targeted the viral RNA. Previous work on these exoribonuclease-resistant RNAs...

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PMID: 33004436
DOI: 10.1261/rna.077065.120

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