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Article

A spectrum of nonsense-mediated mRNA decay efficiency along the degree of mutational constraint

2023-06-30

Abstract excerpt

<title>Abstract</title> <p>A landmark study has proposed several factors on nonsense-mediated mRNA decay (NMD) efficiency using matched genome and transcriptome data of human cancer but was highly affected by random variance caused by the indirect measure of NMD efficiency. In this study, using a more direct, allele-specific expression-based measure of NMD efficiency, a more precise NMD efficiency model was devel...

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Literature Corpus work
9581ac86-50b2-5d28-be2b-8a57bd330345
DOI
10.21203/rs.3.rs-3057064/v1
Open publication

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A spectrum of nonsense-mediated mRNA decay efficiency along the degree of mutational constraintDOI 10.21203/rs.3.rs-3057064/v1
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