Article

Long-read sequencing-based atlas of tissue-specific expression of Drp1 transcript variants

2025-10-07

Abstract excerpt

Dynamin-related protein 1 (Drp1), encoded by DNM1L , is essential for mitochondrial fission, but its functional roles remain unclear due to isoform-specific effects from alternative splicing. Short-read RNA sequencing fails to resolve full-length isoforms involving distant exons, limiting our understanding. Here, we applied targeted long-read sequencing to profile full-length DNM1L transcripts in human left vent...

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Literature Corpus work: 955efd84-6544-5f71-844b-6e42bbb0df69
DOI: 10.1101/2025.10.06.680828

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