Article

Small gene networks can delineate immune cell states and characterize immunotherapy response in melanoma

2022-07-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Single-cell sequencing studies have elucidated some of the underlying mechanisms responsible for immune checkpoint inhibitor (ICI) response, but are difficult to implement as a general strategy or in a clinical diagnostic setting. In contrast, bulk RNAseq is now routine for both research and clinical applications. Therefore, our analysis extracts small transcription factor-d...

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Literature Corpus work: 955d3453-7fcf-5bc6-aa53-f185afc08f63
DOI: 10.1101/2022.07.11.498823

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