Article

synpact: accurate, memory-light PacBio HiFi read mapping via a hierarchy of locally-consistent syncmer blocks

2026-07-02

Abstract excerpt

Motivation: Mapping PacBio HiFi reads is a routine task and serves as a central step in many bioinformatics analyses. However, the most accurate long-read mappers have a high memory consumption and are slow. Some light-weight mappers have been proposed for faster runtime, but their accuracy is not comparable to state-of-the-art mappers. With the increasing number of available reference sequences, memory-efficient...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 954d1a4a-fb5e-5081-8cf7-3a6c0aa4453d
DOI: 10.64898/2026.06.28.735066

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

synpact: accurate, memory-light PacBio HiFi read mapping via a hierarchy of locally-consistent syncmer blocksDOI 10.64898/2026.06.28.735066Read

Fast and accurate read mapping with approximate seeds and multiple backtracking.Semantic proximity Read

S-conLSH: Alignment-free gapped mapping of noisy long readsSemantic proximity Read

Rapid-PFP: Accelerating Prefix-Free Parsing with GPU ParallelismSemantic proximity Read

MAtCHap: an ultra fast algorithm for solving the single individual haplotype assembly problemSemantic proximity Read

mrsFAST-Ultra: a compact, SNP-aware mapper for high performance sequencing applications.Semantic proximity Read

PerFSeeB: Designing Long High-weight Single Spaced Seeds for Full Sensitivity Alignment with a Given Number of MismatchesSemantic proximity Read

PolyCluster: Minimum Fragment Disagreement Clustering for Polyploid Phasing.Semantic proximity Read

Genome misassembly detection using Stash: A data structure based on stochastic tile hashingSemantic proximity Read

A general and extensible algorithmic framework to biological sequence alignment across scales and applicationsSemantic proximity Read

Alignment of Single-Molecule Sequencing Reads by Enhancing the Accuracy and Efficiency of Locality-Sensitive HashingSemantic proximity Read

HyPo: Super Fast & Accurate Polisher for Long Read Genome AssembliesSemantic proximity Read

mm2-gb: GPU Accelerated Minimap2 for Long Read DNA MappingSemantic proximity Read