Article

S-conLSH: Alignment-free gapped mapping of noisy long reads

2019-10-10

Abstract excerpt

<h4>Motivation</h4> The advancement of SMRT technology has unfolded new opportunities of genome analysis with its longer read length and low GC bias. Alignment of the reads to their appropriate positions in the respective reference genome is the first but costliest step of any analysis pipeline based on SMRT sequencing. However, the state-of-the-art aligners often fail to identify distant homologies due to lack o...

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Literature Corpus work: acf3ef4a-7b25-5ace-97c3-db66a971d39c
DOI: 10.1101/801118

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