Article
mrsFAST-Ultra: a compact, SNP-aware mapper for high performance sequencing applications.
Nucleic acids research - 1 Jul 2014
Hach Faraz, Sarrafi Iman, Hormozdiari Farhad, Alkan Can, Eichler Evan E, Sahinalp S Cenk
Abstract excerpt
High throughput sequencing (HTS) platforms generate unprecedented amounts of data that introduce challenges for processing and downstream analysis. While tools that report the 'best' mapping location of each read provide a fast way to process HTS data, they are not suitable for many types of downstream analysis such as structural variation detection, where it is important to report multiple mapping loci for each...
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