Article

Cytokine-induced Chromatin Accessibility in Whole Blood Neutrophils Links to Sepsis Transcriptional States

2026-02-05

Abstract excerpt

<h4>Background</h4> Neutrophils play an important role in the immune system and sense environmental perturbations including pathogens. Upon pathogen detection, neutrophils extrude their chromatin, forming neutrophil extracellular traps (NETs) trapping and removing pathogens. Previous studies have shown that controlled chromatin decondensation occurs during NET formation, reflecting NET inducing pathways, and the...

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Literature Corpus work: 950c9efd-d7c0-5192-945f-cac8f42578e3
DOI: 10.64898/2026.02.03.703332

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