Article

A humanized mouse model system mimics prenatal Zika infection and reveals premature differentiation of neural stem cells

2025-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Zika, a mosquito-borne flavivirus, has been found in 87 countries and territories. Global outbreaks peaked in 2016. Prenatal infection of Zika virus was found to be associated with microcephaly, arthrogryposis, intracranial calcifications, fetal growth restriction, and fetal demise. The most severely affected children were diagnosed with congenital Zika syndrome, which impacts thousands worldwid...

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Identifiers and source

Literature Corpus work: 95059813-210b-56dc-97b5-69c14f73f6ea
DOI: 10.1101/2025.02.21.639556

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