In utero infection of Zika virus leads to abnormal central nervous system development in mice

Abstract excerpt

The World Health Organization has declared ZIKA virus (ZIKV) a global public health emergency, prompted by the association of ZIKV infections with severe brain abnormalities in the human fetus. ZIKV preferentially targets human neuronal precursor cells (NPCs) in both monolayer and cortical brain organoid culture systems and stunts their growth. Although ZIKV is well recognized to cause microcephaly, there is no...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mosquito-borne diseases and control