Article

Replication of early and recent Zika virus isolates throughout mouse brain development

2017-08-17

Abstract excerpt

Fetal infection with Zika virus (ZIKV) can lead to congenital Zika virus syndrome (cZVS), which includes cortical malformations and microcephaly. The aspects of cortical development that are affected during virus infection are unknown. Using organotypic brain slice cultures generated from embryonic mice of various ages, sites of ZIKV replication including the neocortical proliferative zone and radial columns, as w...

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Literature Corpus work: f690d8dd-3abd-5599-bbf4-180af0c296bc
DOI: 10.1101/177816

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