Article

Identification of a minimal <i>Alu</i> domain required for retrotransposition

2024-12-16

Abstract excerpt

<h4>ABSTRACT</h4> Alu elements are primate-specific retrotransposon sequences that comprise ∼11% of human genomic DNA. Alu sequences contain an internal RNA polymerase III promoter and the resultant Alu RNA transcripts mobilize by a replicative process termed retrotransposition. Alu retrotransposition requires the Long INterspersed Element-1 (LINE-1) open reading frame 2-encoded protein (ORF2p). Current models...

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Literature Corpus work: 94f84eea-6637-5c0c-987f-22d157bab805
DOI: 10.1101/2024.12.16.628748

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