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Article

The impact of retrotransposons on human genome evolution.

Nature reviews. Genetics - 1 Oct 2009

Cordaux Richard, Batzer Mark A

Abstract excerpt

Their ability to move within genomes gives transposable elements an intrinsic propensity to affect genome evolution. Non-long terminal repeat (LTR) retrotransposons--including LINE-1, Alu and SVA elements--have proliferated over the past 80 million years of primate evolution and now account for approximately one-third of the human genome. In this Review, we focus on this major class of elements and discuss the...

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Identifiers

PMID: 19763152
DOI: 10.1038/nrg2640
PMCID: PMC2884099

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