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Article

Effect of metformin on the proliferation, apoptosis, invasion and autophagy of ovarian cancer cells

24 Jul 2019

Abstract excerpt

The present study evaluated the effect of metformin on the SKOV3 ovarian cancer cell line and investigated the underlying mechanism. The inhibitory rate of SKOV3 cells was analyzed by MTT assay. SKOV3 cell apoptosis rate was quantitatively measured using flow cytometry. The effect of metformin on intracellular autophagosomes was observed using electron microscopy. The migration and invasion capabilities of SKOV3...

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PMID: 31452705
DOI: 10.3892/etm.2019.7803

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