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Network pharmacology-based investigation and experimental validation of the mechanism of Metformin in the treatment of acute myeloid leukemia

2024-03-29

Abstract excerpt

<title>Abstract</title> <p>Metformin，a widely used anti-diabetic agent, has shown significant anti-cancer properties as reported in in various cancers, including acute myeloid leukemia. However, the detailed mechanisms by which metformin influences acute myeloid leukemia remain unrevealed. Employing a synergistic approach of network pharmacology and experimental validation, this study systematically identifies an...

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Literature Corpus work
07a1d21b-9eb3-52da-b20c-45912f573964
DOI
10.21203/rs.3.rs-4167425/v1
Open publication

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Network pharmacology-based investigation and experimental validation of the mechanism of Metformin in the treatment of acute myeloid leukemiaDOI 10.21203/rs.3.rs-4167425/v1
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