Article
Microglial ERK signaling is a critical regulator of pro-inflammatory immune responses in Alzheimer’s disease
2019-10-08
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Background</h4> The mitogen-activated protein kinase (MAPK) pathway is a central regulator of gene expression, pro-survival signaling, and inflammation. However, the importance of MAPK pathway signaling in regulating microglia-mediated neuroinflammation in Alzheimer’s Disease (AD) remains unclear. Here we examined the role of MAPK signaling in microglia using pre-clinical in-vitro and in-...
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Identifiers and source
- Literature Corpus work
- 94c91a25-d939-5edf-bf05-ac9e12f77cc7
- DOI
- 10.1101/798215