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Microglial Transforming Growth Factor-β Signaling in Alzheimer’s Disease

7 Mar 2024

Abstract excerpt

Novel technologies such as single-cell RNA and single-nucleus RNA sequencing have shed new light on the complexity of different microglia populations in physiological and pathological states. The transcriptomic profiling of these populations has led to the subclassification of specific disease-associated microglia and microglia clusters in neurodegenerative diseases. A common profile includes the downregulation...

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PMID: 38542077
DOI: 10.3390/ijms25063090

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