Article

Cell generation dynamics underlying naïve T cell homeostasis in adult humans

2019-05-13

Abstract excerpt

<h4>ABSTRACT</h4> Thymic involution and proliferation of naive T cells both contribute to shaping the naive T cell repertoire as humans age, but a clear understanding of the roles of each throughout a human lifespan has been difficult to determine. By measuring nuclear bomb test-derived 14 C in genomic DNA we determined the turnover rates of CD4 + and CD8 + naïve T cell populations and defined their dynamics i...

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Literature Corpus work: 94c49e2b-501c-508a-8096-6039259e552c
DOI: 10.1101/635995

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