Article

Using genomics and population genetics to understand genetic variation in Malawi Plasmodium falciparum clinical isolates

2013-01-01

Abstract excerpt

The natural selection imposed by host immunity and antimalarial drugs has driven extensive adaptive evolution in Plasmodium falciparum, leading to an ever-changing landscape of genetic variation. We have carried out whole-genome sequencing of 93 P. falciparum clinical isolates from Malawi and used population genetic methods to investigate the genetic diversity and regions under selection. In addition, by computing...

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Literature Corpus work: 94ba9a13-3788-56fc-b376-6d323d5145c3
DOI: 10.17638/00015753

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