Article

A bioinformatic analysis of malaria host and pathogen genomics

2019-01-01

Abstract excerpt

Malaria is a significant global disease caused by infection with parasites of the Plasmodium genus, which resulted in an estimated 216 million cases and 445,000 deaths in 2016 alone. Co-evolution of Plasmodium parasites and their human hosts has shaped both genomes for thousands of years. In this thesis I describe my work identifying and characterising novel genomic variants and selection signals associated with h...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ad2f9f4a-3c23-5e28-947b-990393afbd1f
DOI: 10.17037/pubs.04653632

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A bioinformatic analysis of malaria host and pathogen genomicsDOI 10.17037/pubs.04653632Read

Pf8: an open dataset of Plasmodium falciparum genome variation in 33,325 worldwide samplesSemantic proximity Read

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samplesSemantic proximity Read

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samplesSemantic proximity Read

An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samplesSemantic proximity Read

Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi.Semantic proximity Read

Genome-wide SNP analysis of Plasmodium falciparum shows differentiation at drug-resistance-associated loci among malaria transmission settings in southern MaliSemantic proximity Read

Using genomics and population genetics to understand genetic variation in Malawi Plasmodium falciparum clinical isolatesSemantic proximity Read

An open dataset of <i>Plasmodium falciparum</i> genome variation in 7,000 worldwide samplesSemantic proximity Read

Genome-wide SNP genotyping of <i>Plasmodium falciparum</i> isolates across Mali reveals major impacts of <i>Pfsa1</i> and PfCRT K76T selections on parasite populationsSemantic proximity Read

Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samplesSemantic proximity Read

An analysis of large structural variation in global Plasmodium falciparum isolates identifies a novel duplication of the chloroquine resistance associated geneSemantic proximity Read

Genome-wide genetic variation and molecular surveillance of drug resistance in Plasmodium falciparum isolates from asymptomatic individuals in Ouélessébougou, Mali.Semantic proximity Read