Article
Genetics and Diagnostic Approach to Lymphoblastic Leukemia/Lymphoma.
Cancer treatment and research - 1 Jan 2021
Afkhami Michelle, Ally Feras, Pullarkat Vinod, Pillai Raju K
Abstract excerpt
Our understanding of the genetics and biology of lymphoblastic leukemia/lymphoma (acute lymphoblastic leukemia, ALL) has advanced rapidly in the past decade with advances in sequencing and other molecular techniques. Besides recurrent chromosomal abnormalities detected by karyotyping or fluorescence in situ hybridization, these leukemias/lymphomas are characterized by a variety of mutations, gene rearrangements...
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