Article

Common Pitfalls in CircRNA Detection and Quantification

2026-02-04

Abstract excerpt

1 Circular RNAs have garnered considerable interest, as they have been implicated in numerous biological processes and diseases. Through their stability, they are often considered promising biomarker candidates or therapeutic targets. Due to the lack of a poly(A) tail, circRNAs are best detected in total RNA-seq data after depleting ribosomal RNA. However, we observe that the application of circRNA detection in th...

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Literature Corpus work: 94830a50-2974-5c31-a666-39b4a57aaf53
DOI: 10.64898/2026.02.02.703185

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