Article

Poly(A) selection limits detection of long and alternatively spliced transcripts compared with rRNA depletion in RNA-Sequencing

2025-12-08

Abstract excerpt

<title>Abstract</title> <p> The eukaryotic transcriptome diversity arises largely from alternative splicing. One of the widely used high-throughput methods to study this diversity is RNA sequencing. RNA sequencing has become a cornerstone of both basic biology and precision medicine, facilitating the quantification of gene and transcript expression, as well as the characterization of alternative splicing events...

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Literature Corpus work: e0874a7e-4873-5e54-bd07-162fa7b8b365
DOI: 10.21203/rs.3.rs-8195045/v1

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