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Nanopore sequencing of full-length circRNAs in human and mouse brains reveals circRNA-specific exon usage and intron retention

2019-03-04

Abstract excerpt

Circular RNA (circRNA) is a poorly understood class of non-coding RNAs, some of which have been shown to be functional important for cell proliferation and development. CircRNAs mainly derive from back splicing events of coding mRNAs, making it difficult to distinguish the internal exon composition of circRNA from the linearly spliced mRNA. To examine the global exon composition of circRNAs, we performed long-read...

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Literature Corpus work
7e5898f5-326a-5a8d-afee-490e6265abb8
DOI
10.1101/567164
Open publication

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Nanopore sequencing of full-length circRNAs in human and mouse brains reveals circRNA-specific exon usage and intron retentionDOI 10.1101/567164
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