Article

Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision

2022-12-06

Abstract excerpt

The detection of circular RNA molecules (circRNAs) is typically based on short-read RNA sequencing data processed by computational detection tools. During the last decade, a plethora of such tools have been developed, but a systematic comparison with orthogonal validation is missing. Here, we set up a circRNA detection tool benchmarking study, in which 16 tools were used and detected over 315,000 unique circRNAs i...

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Literature Corpus work: 8057698e-86e6-5771-aaa2-669029eddb14
DOI: 10.1101/2022.12.06.519083

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