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Statin treatment effectiveness and the <i>SLCO1B1</i>*5 reduced function genotype: long-term outcomes in women and men

2021-10-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> To estimate the effect of the SLCO1B1 *5 genotype (decreases statin transport) on cholesterol control and treatment duration in male and female primary care patients prescribed common statin medications. <h4>Methods and Analysis</h4> 69,185 European-ancestry UK Biobank cohort participants prescribed simvastatin or atorvastatin (aged 40 to 79 years at first prescription; treatme...

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Literature Corpus work
944ec001-461b-5907-8525-72c0cca8ea05
DOI
10.1101/2021.10.12.21264886
Open publication

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Statin treatment effectiveness and the <i>SLCO1B1</i>*5 reduced function genotype: long-term outcomes in women and menDOI 10.1101/2021.10.12.21264886
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