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Article

SLCO1B1*5 is protective against non-senile cataracts in cohort prescribed statins: analysis in a British-South Asian cohort.

The pharmacogenomics journal - 1 Sept 2023

Magavern Emma F, van Heel David A, Smedley Damian, Caulfield Mark J

Abstract excerpt

BACKGROUND: Reported association between statin use and cataract risk is controversial. The SLCO1B1 gene encodes a transport protein responsible for statin clearance. The aim of this study was to investigate a possible association between the SLCO1B1*5 reduced function variant and cataract risk in statin users of South Asian ethnicity. METHODS: The Genes & Health cohort consists of British-Bangladeshi and...

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PMID: 37221222
DOI: 10.1038/s41397-023-00307-w
PMCID: PMC10506906

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