Article

Understanding the causes and consequences of low statin adherence: evidence from UK Biobank primary care data

2025-01-25

Abstract excerpt

<h4>Background</h4> Statins are commonly prescribed to lower LDL cholesterol. Clinical guidelines recommend 30-50% reduction within 3 months, yet many patients do not achieve this. We investigated the impact of patient characteristics and genetics on LDL-c reduction, treatment adherence, and adverse clinical outcomes. <h4>Methods</h4> We analysed 76,000 UK Biobank participants prescribed atorvastatin or simvastati...

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Literature Corpus work: 30a86250-2654-5afd-8305-4bd38de2548e
DOI: 10.1101/2025.01.23.25321011

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