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Article

Pfs47 as a Malaria Transmission-Blocking Vaccine Target

11 Jul 2022

Abstract excerpt

Transmission-blocking vaccines (TBVs), pioneered by Richard Carter and others, aim to prevent parasite development in the mosquito vector and are a promising new tool for malaria elimination. Pfs47, recently identified as a TBV target, is a three-domain 6-cysteine protein on the surface of Plasmodium falciparum sexual stages. Pfs47 allows the parasite to evade mosquito immunity and is key for P. falciparum...

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PMID: 35895390
DOI: 10.4269/ajtmh.21-1325

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