Article

From Molecular Biology to Epithelial Carcinogenesis

2021-07-05

Abstract excerpt

The theory of the origin of carcinomas suggests that neoplasias from epithelial tissues are the consequence of the reactivation of developmental programs. It proposes a model in which the epithelial cells undergo cellular transitions due to replicative senescence and inflammation towards a mesenchymal-undifferentiated phenotype with cancerous behavior. The conserved pattern of histological progression and the mole...

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Literature Corpus work: 93ac9118-d71e-5548-8bdd-20ec390715c3
DOI: 10.20944/preprints202107.0090.v1

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