Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Revisiting Epithelial Carcinogenesis

4 Jul 2022

Abstract excerpt

The origin of cancer remains one of the most important enigmas in modern biology. This paper presents a hypothesis for the origin of carcinomas in which cellular aging and inflammation enable the recovery of cellular plasticity, which may ultimately result in cancer. The hypothesis describes carcinogenesis as the result of the dedifferentiation undergone by epithelial cells in hyperplasia due to replicative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Epigenetics and DNA Methylation
Share to FOXO transcription factor regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35806442
DOI: 10.3390/ijms23137437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Revisiting Epithelial CarcinogenesisPMID 35806442Read ↗

Revisiting Epithelial CarcinogenesisSemantic proximity Read ↗

On the Origin of CarcinomaSemantic proximity Read ↗

From Molecular Biology to Epithelial CarcinogenesisSemantic proximity Read ↗

Cancer and aging: a model for the cancer promoting effects of the aging stroma.Semantic proximity Read ↗

The Aging–Cancer Cycle: Mechanisms and Opportunities for InterventionSemantic proximity Read ↗

Integrating epithelial cancer, aging stroma and cellular senescence.Semantic proximity Read ↗

Skin Cancer Microenvironment: What We Can Learn from Skin Aging?Semantic proximity Read ↗

Wnt-signaling and senescence: A tug of war in early neoplasia?Semantic proximity Read ↗

Ageing as an Important Risk Factor for Cancer.Semantic proximity Read ↗

Aging and cancerSemantic proximity Read ↗

Oncogenic senescence: a multi-functional perspectiveSemantic proximity Read ↗

Science of cancer and aging.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.