Article

Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes

2019-04-07

Abstract excerpt

Hepatocytes are regarded as the only effective cell source for cell transplantation to treat liver diseases; however, their availability is limited due to a donor shortage. Thus, a novel cell source must be developed. We recently reported that mature rodent hepatocytes can be reprogrammed into progenitor-like cells with a repopulative capacity using small molecule inhibitors. Here, we demonstrate that hepatic prog...

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Literature Corpus work: 93487efc-1838-58cd-9e84-314e44144f1a
DOI: 10.1101/601922

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