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Guide to the Assessment of Mature Liver Gene Expression in Stem Cell-Derived Hepatocytes

24 May 2019

Abstract excerpt

Differentiation of stem cells to hepatocyte-like cells (HLCs) holds great promise for basic research, drug and toxicological investigations, and clinical applications. There are currently no protocols for the production of HLCs from stem cells, such as embryonic stem cells or induced pluripotent stem cells, that produce fully mature hepatocytes with a wide range of mature hepatic functions. This report describes...

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PMID: 31122128
DOI: 10.1089/scd.2019.0064

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