Article

Cryopreserved cGMP-compliant human pluripotent stem cells-derived immature hepatic progenitors rescue mice from acute liver failure

2022-09-26

Abstract excerpt

Liver transplantation remains the only curative treatment for end-stage liver diseases. Unfortunately, there is a drastic organ donor shortage. Hepatocyte transplantation emerged as a viable alternative to liver transplantation. In light of their unique expansion capabilities and their potency to be driven towards a chosen cell fate, pluripotent stem cells (PSC) are extensively studied as an unlimited cell source...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 334c6f12-853f-58b2-bdbd-365853fe5343
DOI: 10.1101/2022.09.26.509491

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cryopreserved cGMP-compliant human pluripotent stem cells-derived immature hepatic progenitors rescue mice from acute liver failureDOI 10.1101/2022.09.26.509491Read

Pluripotent Stem Cell-Derived Hepatocyte-like Cells: Induction Methods and ApplicationsSemantic proximity Read

The Application of Induced Pluripotent Stem Cells Against Liver Diseases: An Update and a ReviewSemantic proximity Read

The Use of Induced Pluripotent Stem Cells for the Study and Treatment of Liver DiseasesSemantic proximity Read

Pluripotent Stem Cell–Derived Hepatocytes: Potential and Challenges in PharmacologySemantic proximity Read

Advances in generating liver cells from pluripotent stem cells as a tool for modeling liver diseasesSemantic proximity Read

Human Induced Pluripotent Stem Cells in HepatologySemantic proximity Read

Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug DiscoverySemantic proximity Read

Production of Human Pluripotent Stem Cell-Derived Hepatic Cell Lineages and Liver Organoids: Current Status and Potential ApplicationsSemantic proximity Read

Production of hepatocytes from human pluripotent stem cells for cell-based therapySemantic proximity Read

Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.Semantic proximity Read

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapySemantic proximity Read

Differentiation of Hepatocytes from Pluripotent Stem CellsSemantic proximity Read