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Article

Sialic Acid Species as a Determinant of the Host Range of Influenza A Viruses

15 Dec 2000

Abstract excerpt

The distribution of sialic acid (SA) species varies among animal species, but the biological role of this variation is largely unknown. Influenza viruses differ in their ability to recognize SA-galactose (Gal) linkages, depending on the animal hosts from which they are isolated. For example, human viruses preferentially recognize SA linked to Gal by the alpha2,6(SAalpha2,6Gal) linkage, while equine viruses favor...

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PMID: 11090182
DOI: 10.1128/jvi.74.24.11825-11831.2000

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