Article
Sialobiology of Influenza: Molecular Mechanism of Host Range Variation of Influenza Viruses
1 Jan 2005
Abstract excerpt
The gene pool of influenza A viruses in aquatic birds provides all of the genetic diversity required for human and lower animals. Host range selection of the receptor binding specificity of the influenza virus hemagglutinin occurs during maintenance of the virus in different host cells that express different receptor sialo-sugar chains. In this paper, functional roles of the hemagglutinin and neuraminidase spikes...
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