Article
Genetics and major depressive disorder: clinical implications for disease risk, prognosis and treatment.
International clinical psychopharmacology - 1 Sept 2020
Fabbri Chiara, Montgomery Stuart, Lewis Cathryn M, Serretti Alessandro
Abstract excerpt
In the post-genomic era, genetics has led to limited clinical applications in the diagnosis and treatment of major depressive disorder (MDD). Variants in genes coding for cytochrome enzymes are included in guidelines for assisting in antidepressant choice and dosing, but there are no recommendations involving genes responsible for antidepressant pharmacodynamics and no consensus applications for guiding diagnosis...
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