Article
IntLIM: integration using linear models of metabolomics and gene expression data.
BMC bioinformatics - 5 Mar 2018
Siddiqui Jalal K, Baskin Elizabeth, Liu Mingrui, Cantemir-Stone Carmen Z, Zhang Bofei, Bonneville Russell, McElroy Joseph P, Coombes Kevin R, Mathé Ewy A
Abstract excerpt
BACKGROUND: Integration of transcriptomic and metabolomic data improves functional interpretation of disease-related metabolomic phenotypes, and facilitates discovery of putative metabolite biomarkers and gene targets. For this reason, these data are increasingly collected in large (> 100 participants) cohorts, thereby driving a need for the development of user-friendly and open-source methods/tools for their...
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