Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RUNX2 prompts triple negative breast cancer drug resistance through TGF-β pathway regulating breast cancer stem cells

13 Jan 2024

Abstract excerpt

Triple-negative breast cancer (TNBC) stands out as the most aggressive subtype within the spectrum of breast cancer. The current clinical guidelines propose treatment strategies involving cytotoxic agents like epirubicin or paclitaxel. However, the emergence of acquired resistance frequently precipitates secondary tumor recurrence or the spread of metastasis. In recent times, significant attention has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38219710
DOI: 10.1016/j.neo.2024.100967

Provenance

PubMed metadata and Literature Corpus relationships.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RUNX2 prompts triple negative breast cancer drug resistance through TGF-β pathway regulating breast cancer stem cellsPMID 38219710Read ↗

Clinically Translatable Approaches of Inhibiting TGF-β to Target Cancer Stem Cells in TNBCSemantic proximity Read ↗

An Insight Into the Cancer Stem Cell Survival Pathways Involved in Chemoresistance in Triple-Negative Breast CancerSemantic proximity Read ↗

Translational drugs targeting cancer stem cells in triple-negative breast cancerSemantic proximity Read ↗

RUNX1 is regulated by androgen receptor to promote cancer stem markers and chemotherapy resistance in triple negative breast cancerSemantic proximity Read ↗

Stemness Phenotype in Tamoxifen Resistant Breast Cancer Cells May be Induced by Interactions Between Receptor Tyrosine Kinases and ERα-66.Semantic proximity Read ↗

RUNX1 and RUNX2 transcription factors function in opposing roles to regulate breast cancer stem cellsSemantic proximity Read ↗

Signaling pathways essential for triple-negative breast cancer stem-like cellsSemantic proximity Read ↗

Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription FactorSemantic proximity Read ↗

Triple-negative breast cancer: understanding Wnt signaling in drug resistanceSemantic proximity Read ↗

TGFβ family signaling in human stem cell self-renewal and differentiationSemantic proximity Read ↗

Cytokines, breast cancer stem cells (BCSCs) and chemoresistanceSemantic proximity Read ↗

How BMP-2 induces EMT and breast cancer stemness through Rb and CD44?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.