Article
Targeting Cellular Signaling Pathways in Breast Cancer Stem Cells and its Implication for Cancer Treatment.
Anticancer research - 1 Nov 2016
Pires Bruno Ricardo Barreto, DE Amorim Ísis Salviano Soares, Souza Layane Duarte E, Rodrigues Juliana Alves, Mencalha Andre Luiz
Abstract excerpt
Breast cancer is a public health problem both in developing and developed countries. The breast cancer stem cell (BCSC) hypothesis has grown in the cancer research community. These BCSCs comprise of a small subpopulation of cells within the tumor mass which exhibit stem cell-like characteristics and have emerged as being responsible for tumor development, recurrence and metastasis in BC. The complexity of control...
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