Article
Characteristics of genomic alterations of lung adenocarcinoma in young never-smokers.
International journal of cancer - 1 Oct 2018
Luo Wenxin, Tian Panwen, Wang Yue, Xu Heng, Chen Lu, Tang Chao, Shu Yang, Zhang Shouyue, Wang Zhoufeng, Zhang Jun, Zhang Li, Jiang Lili, Liu Lunxu, Che Guowei, Guo Chenglin, Zhang Hong, Wang Jiali, Li Weimin
Abstract excerpt
Non-small-cell lung cancer (NSCLC) has been recognized as a highly heterogeneous disease with phenotypic and genotypic diversity in each subgroup. While never-smoker patients with NSCLC have been well studied through next generation sequencing, we have yet to recognize the potentially unique molecular features of young never-smoker patients with NSCLC. In this study, we conducted whole genome sequencing (WGS) to...
Topics
- Adenocarcinoma of Lung
- Adult
- Age Factors
- Biomarkers, Tumor
- Carcinoma, Non-Small-Cell Lung
- Female
- Follow-Up Studies
- High-Throughput Nucleotide Sequencing
- Humans
- Lung Neoplasms