Article

Unraveling the Genetic Blueprint of Doxorubicin-Induced Cardiotoxicity Through Systems Genetics Approaches

2025-04-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Anthracycline-induced cardiotoxicity (ACT) is a significant concern for cancer survivors. The genetic basis of ACT remains unclear because of the impact of lifestyle and environmental factors in human studies. This study employs a murine genetic reference population (GRP) of BXD recombinant inbred strains, derived from DBA/2J (D2) and C57BL/6J (B6) crosses, to ma...

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Literature Corpus work: 9285d55a-b2c6-52bf-b79f-9a461a2f8a71
DOI: 10.21203/rs.3.rs-6224399/v1

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