Article

Morphogen-Lineage Selector Interactions During Surface Epithelial Commitment

2018-06-16

Abstract excerpt

Human embryonic stem cell (hESC) differentiation promises advances in regenerative medicine 1–3 , yet conversion of hESCs into tissues such as keratinocytes requires a better understanding of epigenetic interactions between the inductive morphogens retinoic acid (RA) and bone morphogenetic protein 4 (BMP), and the master regulator p63 4,5 . Here we develop a robust, defined, keratinocyte differentiation system,...

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Literature Corpus work: 926843b4-d51c-5d13-9bab-1a0e91141404
DOI: 10.1101/348839

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