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Article

Notch signaling represses p63 expression in the developing surface ectoderm

8 Aug 2013

Abstract excerpt

The development of the mature epidermis requires a coordinated sequence of signaling events and transcriptional changes to specify surface ectodermal progenitor cells to the keratinocyte lineage. The initial events that specify epidermal keratinocytes from ectodermal progenitor cells are not well understood. Here, we use both developing mouse embryos and human embryonic stem cells (hESCs) to explore the...

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PMID: 23924630
DOI: 10.1242/dev.093948

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