Article

Sympathetic-like-Integrated Engineered Heart Tissue Models AGEs-Induced Adverse Remodeling

2025-11-10

Abstract excerpt

<title>Abstract</title> <p>Background Cardiovascular metabolic diseases (CMDs) are a major contributor to global mortality and disability, yet their pathogenesis remains incompletely understood, partly because existing in vitro models fail to capture disease complexity. Conventional engineered heart tissues (EHT), which typically contain only a limited set of cell types and lack neural components, cannot replicat...

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Literature Corpus work: 921d548a-c7e1-5db6-9078-c42d4649a659
DOI: 10.21203/rs.3.rs-7937768/v1

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